Ford L, Carter GP, Wang Q, Seemann T, Sintchenko V, Glass K, Williamson DA, Howard P, Valcanis M, Castillo CF, Sait M, Howden BP, Kirk MD. Incorporating whole genome sequencing into public health surveillance: Lessons from prospective sequencing of Salmonella Typhimurium in Australia. Foodborne Pathogens and Disease 2018; 15(3):161-167.
In Australia, the incidence of Salmonella Typhimurium has increased dramatically over the past decade. Whole-genome sequencing (WGS) is transforming public health microbiology, but poses challenges for surveillance. To compare WGS-based approaches with conventional typing for Salmonella surveillance, we performed concurrent WGS and multilocus variable-number tandem-repeat analysis (MLVA) of Salmonella Typhimurium isolates from the Australian Capital