Williams RD, Markus AF, Yang C, Duarte Salles T, Duvall SL, Falconer T, Jonnagaddala J, Kim C, Rho Y, Williams A, Alberga A, An MH, Aragón M, Areia C, Burn E, Choi Y, Drakos I, Fernandes Abrahão M, Fernández-Bertolín S, Hripcsak G, Kaas-Hansen B, Kandukuri P, Kors JA, Kostka K, Liaw S-T, Lynch KE, Matheny ME, Machnicki G, Morales D, Nyberg F, Park RW, Prats-Uribe A, Pratt N, Rao G, Reich CG, Rivera M, Seinen T, Shoaibi A, Spotnitz ME, Steyerberg EW, Suchard MA, You SC, Zhang L, Zhou L, Ryan PB, Prieto-Alhambra D, Reps JM, Rijnbeek PR. Seek COVER: Development and validation of a personalized risk calculator for COVID-19 outcomes in an international network. medRxiv. 2020:2020.05.26.20112649. preprint
Objective: To develop and externally validate COVID-19 Estimated Risk (COVER) scores that quantify a patient’s risk of hospital admission (COVER-H), requiring intensive services (COVER-I), or fatality (COVER-F) in the 30-days following COVID-19 diagnosis. Methods: We analyzed a federated network of electronic medical records and administrative claims data from 14 data sources and 6 countries. We