Clark, J., Scott, A.M. and Glasziou, P., 2020. Not All Systematic Reviews Can Be Completed in 2 Weeks-But Many Can Be (And Should Be). Journal of Clinical Epidemiology, pp.S0895-4356.

Dear Editors, We would like to thank Yan et al. for providing us with an opportunity to expand on the applicability of our 2-week systematic review (2weekSR) processes [1]. Yan et al. correctly point out that “it is important to recognize not all systematic reviews (SRs) are created equal and complexity of the [SR] topic

Godinho MA, Borda A, Kostkova P, Molnar A, Liaw ST. ‘Serious Games’ for unboxing Global Digital Health policymaking. BMJ Stel 2020; 0:1–2. doi:10.1136/bmjstel-2020-000606

The news headlines report daily on the global political impacts of digital technology: the secondary use of social media data has been implicated in election meddling, though the complex issues surrounding data governance, data ownership and the ethics of personalised advertising remain to be addressed. Meanwhile, digital automation drives unemployment and income inequality, even as

Liaw ST, Georgiou A, Marin H. Evaluation of digital health and information technology in primary care. Int J Med Informatics 2020. DOI:

Primary care is where the health care system meets the people – the first point of care for the citizenry. General practice and primary care DH&IT tools are essential strategies to strengthen health systems to achieve health priorities and universal health coverage and sustainable development goals. While primary care DH&IT systems are just as if

Struelens MJ, Sintchenko V. Pathogen genomics: Empowering infectious disease surveillance and outbreak investigations. Frontiers in Public Health 2020 May 19;8:179.

Comparative microbial genomics analysis by high-throughput whole-genome sequencing (WGS) offers exquisite resolution for epidemiological investigations of infectious disease. This approach has revolutionized outbreak detection and monitoring of transmission dynamics of infectious agents and antimicrobial resistance across humans, animals, and environment. The objective of this Research Topic was to assemble articles on genomic epidemiological approaches to

Moynihan R, Sanders S, Michaleff ZA, Scott A, Clark J, To EJ, Jones M, Kitchener E, Fox M, Johansson M, Lang E, Duggan A, Scott I, Albarqouni L. Pandemic impacts on healthcare utilisation: a systematic review. medRxiv. 2020:2020.10.26.20219352.

Objectives: To determine the extent and nature of changes in utilisation of healthcare services during COVID-19 pandemic. Design: Systematic review. Eligibility: Eligible studies compared utilisation of services during COVID-19 pandemic to at least one comparable period in prior years. Services included visits, admissions, diagnostics, and therapeutics. Studies were excluded if from single-centres or studied only

Byambasuren O, Dobler CC, Bell K, Rojas DP, Clark J, McLaws M-L, Glasziou P. Comparison of seroprevalence of SARS-CoV-2 infections with cumulative and imputed COVID-19 cases: systematic review. medRxiv. 2020:2020.07.13.20153163. preprint

Background. Accurate seroprevalence estimates of SARS-CoV-2 in different populations could clarify the extent to which current testing strategies are identifying all active infection, and hence the true magnitude and spread of the infection. Our primary objective was to identify valid seroprevalence studies of SARS-CoV-2 infection and compare their estimates with the reported and imputed COVID-19

Byambasuren O, Cardona M, Bell K, Clark J, McLaws M-L, Glasziou P. Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: systematic review and meta-analysis. medRxiv. 2020:2020.05.10.20097543.

Background: The prevalence of true asymptomatic COVID-19 cases is critical to policy makers considering the effectiveness of mitigation measures against the SARS-CoV-2 pandemic. We aimed to synthesize all available research on the asymptomatic rates and transmission rates where possible. Methods: We searched PubMed, Embase, Cochrane COVID-19 trials, and Europe PMC (which covers pre-print platforms such

Bakhit M, Krzyzaniak N, Scott AM, Clark J, Glasziou P, Del Mar C. Downsides of face masks and possible mitigation strategies: a systematic review and meta-analysis. medRxiv. 2020:2020.06.16.20133207.

Objective To identify, appraise, and synthesise studies evaluating the downsides of wearing facemasks in any setting. We also discuss potential strategies to mitigate these downsides. Methods PubMed, Embase, CENTRAL, EuropePMC were searched (inception-18/5/2020), and clinical registries were searched via CENTRAL. We also did forward-backward citation search of the included studies. We included randomised controlled trials

Albarqouni L, Byambasuren, O., Clark, J., Scott, A.M., Looke, DGlasziou, P. Does Copper treating of commonly touched surfaces reduce healthcare acquired infections? A Systematic Review and meta-analysis. Journal of Hospital Infection. (106/4) p765-773, 2020

Background Healthcare-acquired infections (HAIs) cause substantial morbidity and mortality. Copper appears to have strong antimicrobial properties under laboratory conditions. Aim To examine the potential effect of copper treatment of commonly touched surfaces in healthcare facilities. Methods Controlled trials comparing the effect of copper-treated surfaces (furniture or bed linens) in hospital rooms compared with standard rooms

Akhtyamova L, Martínez P, Verspoor K, Cardiff J. (2020) Testing Contextualized Word Embeddings to Improve NER in Spanish Clinical Case Narratives. IEEE Access.

In the Big Data era, there is an increasing need to fully exploit and analyze the huge quantity of information available about health. Natural Language Processing (NLP) technologies can contribute by extracting relevant information from unstructured data contained in Electronic Health Records (EHR) such as clinical notes, patients’ discharge summaries and radiology reports. The extracted

Wilson DJ, and The CRyPTIC Consortium. GenomeMap: Within-species genome-wide dn/ds estimation from over 10,000 genomes. Molecular Biology and Evolution 2020;37(8):2450-2460.

The dN/dS ratio provides evidence of adaptation or functional constraint in protein-coding genes by quantifying the relative excess or deficit of amino acid-replacing versus silent nucleotide variation. Inexpensive sequencing promises a better understanding of parameters, such as dN/dS, but analyzing very large data sets poses a major statistical challenge. Here, I introduce genomegaMap for estimating

Staccini P, Lau AYS; Social Media, Research, and Ethics: Does Participant Willingness Matter?. Section Editors for the IMIA Yearbook Section on Consumer Health Informatics and Education. Yearb Med Inform. 2020 Aug;29(1):176-183. doi: 10.1055/s-0040-1702022. Epub 2020 Aug 21.

Objective : To summarise the state of the art published in 2019 in consumer health informatics and education, with a special emphasis on “Ethics and Health Informatics”. Methods : We conducted a systematic search of articles published in PubMed using a predefined set of queries, which identified 368 potential articles for review. These articles were

Sittig DF, Wright A, Coiera E, et al. Current challenges in health information technology-related patient safety. Health Informatics J 2020;26(1):181-89 doi: 10.1177/1460458218814893[published Online First: Epub Date]

We identify and describe nine key, short-term, challenges to help healthcare organizations, health information technology developers, researchers, policymakers, and funders focus their efforts on health information technology-related patient safety. Categorized according to the stage of the health information technology lifecycle where they appear, these challenges relate to (1) developing models, methods, and tools to enable